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Jon Waataja
Ph.D. 2007
Present Position: Research Scientist at EnteroMedics doing Preclinical Research
E-mail: jwaataja@enteromedics.com |
Undergraduate Institution and Major/Degree:
Graduate Major Advisor(s):
Graduate Research Description:
I am interested in studying synaptic changes that occur during excitotoxic-induced neuroegeneration. Excitotoxicity is caused by the excess release of glutamate and is thought to contribute to many neurodegenerative disorders including stroke, HIV associated dementia and Alzheimer's disease. I have developed a technique to track synaptic changes along with cell viability of single neurons over time. This has given us insights into the temporal relationship as well as mechanisms of synapse loss related to cell death.
Graduate Lab Rotations:
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David Redish
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Karen Ashe
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Stan Thayer
Conferences Attended:
Conference Presentations:
Thesis Publications:
Recent Publications:
- Gilbert GL, Kim HJ, Waataja JJ, Thayer SA. Delta9-tetrahydrocannabinol protects hippocampal neurons from excitotoxicity. Brain Res. 2007 Jan 12;1128(1):61-9. Epub 2006 Nov 30.
- Song JH, Waataja JJ, Martemyanov KA. Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP.
J Biol Chem. 2006 Jun 2;281(22):15361-9. Epub 2006 Mar 30.
- Kim HJ, Waataja JJ, Thayer SA. (Submitted) Cannabinoids inhibit network driven synapse loss between hippocampal neurons in culture.
Graduate Committee Members:
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Eric Newman
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Paul Letourneau
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Johnathan Merchant
Professional Memberships: Home Town:
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