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Undergraduate Institution and Major/Degree:
Major Advisor(s):
Research Description:
Peripherally applied opioids are ineffective under normal conditions.
However, peripheral opioid receptors become functionally competent following inflammatory insult. Our lab employs teased fiber electrophysiological techniques to examine what fiber and receptor types are responsible for mediating opioid analgesia after inflammation.
Increased understanding of how the endogenous peripheral opioid system becomes activated may lead to future pain treatments that take advantage of this system, thereby avoiding the risk of abuse and centrally mediated side effects associated with current opioid therapy.
Lab Rotations:
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Lorene Lanier
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S. Hossein Fatemi
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Mark Thomas
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Chris Honda
Courses Taken Beyond the Core Courses:
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PSY 8960 - Synaptic Plasticity in Drug Abuse
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STAT 5021 - Statistical Analysis
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PHCL 5462 - Neuroscience of Drugs of Abuse
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PHCL 8221 - Neurobiology of Pain and Analgesia
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CMB 8361 - Neuro-Immune Interactions
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PHCL 8208 Neuropsychopharmacology
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PHCL 8320 Readings in Neurobiology (Karolinska pain course)
Graduate Level Minor:
Conferences Attended:
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Spring Pain Research Conference - 2006, 2008
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Midwest Pain Interest Group annual meeting - 2005
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Society for Neuroscience annual meeting - 2004, 2007, 2008
Abstracts:
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Schramm C and Honda CN (2008) The function of peripheral mu opioid
receptors is enhanced by delta opioid receptor agonists, Society for
Neuroscience Abstracts, Washington, D.C.
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Satterfield C, Schramm CL, Honda CN (2007) The functional state of peripheral mu-opioid receptors is differentially regulated during early and later stages of inflammation, Society for Neuroscience Abstracts, San Diego, CA.
Committee Members:
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Don Simone - chair
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Chris Honda - advisor
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Stan Thayer
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Carolyn Fairbanks
Awards and Honors:
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PharmacoNeuroImmunology Training Grant, 2007-present
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Ruth L. Kirschstein National Research Service Award 2004-2005
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National Merit Scholarship 1999-2003
Professional Memberships:
Home Town:
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