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Christopher N. Honda, Ph.D.
Professor, Department of Neuroscience
E-mail: cnhonda@umn.edu |
Research Interests:
The skin and deep tissues comprise a vital interface between our
bodies and our surroundings. The senses of touch and pain are especially
critical in our interactions with the environment. Our research
interests are centered on functional and morphological mechanisms
that underlie the sense of touch, and there is a particular emphasis
in our laboratory on neuronal events and neural pathways that may
contribute to the complex sensory experience of pain.
A combination of anatomical, immunohistochemical, and electrophysiological
techniques are employed to establish basic relationships between
neuronal structure, cytochemistry and function. We are applying
these techniques to the study of individual neurons within these
sensory systems in the peripheral nervous system as well as the
spinal cord and thalamus.
Selected Publications:
Wenk HN, Brederson JD, Honda CN. Morphine directly inhibits nociceptors in inflamed skin. J Neurophysiol. 2006 Apr;95(4):2083-97.
Simone DA, Zhang X, Li J, Zhang JM, Honda CN, LaMotte RH, Giesler GJ Jr. Comparison of responses of primate spinothalamic tract neurons to pruritic and algogenic stimuli. J Neurophysiol. 2004 Jan;91(1):213-22.
Truong H, McGinnis L, Dindo L, Honda CN, Giesler GJ Jr. Identification of dorsal root ganglion neurons that innervate the common bile duct of rats. Exp Brain Res. 2004 Apr;155(4):477-84.
Wenk HN, Nannenga MN, Honda CN. Effect of morphine sulphate eye drops on hyperalgesia in the rat cornea. Pain. 2003 Oct;105(3):455-65.
Wenk HN, Honda CN. Silver nitrate cauterization: characterization of a new model of corneal inflammation and hyperalgesia in rat. Pain. 2003 Oct;105(3):393-401.
Current Graduate Students:
Catherine Satterfield
(Neuroscience, University of Minnesota).
Cicely Schramm (Neuroscience, University of Minnesota).
Former Graduate Students:
Heather Wenk (Ph.D. 2002, Neuroscience,
University of Minnesota).
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