A. David Redish, Ph.D.

Professor, Department of Neuroscience

Alfred P. Sloan Research Fellow for 2003 - 2005

E-mail: redish@umn.edu

Personal Webpage: http://redishlab.neuroscience.umn.edu/

Research Interests:

Modern neuroscience sees the brain as an information-processing device. Understanding how the brain processes information requires understanding the representations used by the network of neurons that compose the brain. However, representations in the brain are distributed: each cell carries only a small portion of the total information. I am interested in questions of how neural structures work together to create systems able to accomplish behavioral tasks.

Our primary current projects are in the interaction between multiple learning systems (such as hippocampus, cortex, and striatum) in the ability to make decisions, particularly deliberative decisions. We have ongoing neurophysiological projects examining the dynamics of neural ensembles
during decision-making processes, computational projects examining
the implications of these processes on addiction and other decision-making dysfunctions, and engineering projects developing new recording systems.

Selected Publications:

(For a comprehensive list of recent publications, refer to PubMed, a service provided by the National Library of Medicine.)

Regier PS, Amemiya S, Redish AD. Hippocampus and subregions of the dorsal striatum respond differently to a behavioral strategy change on a spatial navigation task. J Neurophysiol. 2015 Sep;114(3):1399-416.

Stott JJ, Redish AD. Representations of Value in the Brain: An Embarrassment of Riches? PLoS Biol. 2015 Jun 18;13(6):e1002174.

Regier PS, Redish AD. Contingency Management and Deliberative Decision-Making Processes. Front Psychiatry. 2015 Jun 1;6:76.

Wikenheiser AM, Redish AD. Decoding the cognitive map: ensemble hippocampal sequences and decision making. Curr Opin Neurobiol. 2015 Jun;32:8-15.

Redish AD, Schultheiss NW, Carter EC. The Computational Complexity of Valuation and Motivational Forces in Decision-Making Processes. Curr Top Behav Neurosci. 2015 May 17.

Schultheiss NW, Redish AD. The compass within. Nat Neurosci. 2015 Apr;18(4):482-3.

Breton YA, Seeland KD, Redish AD. Aging impairs deliberation and behavioral flexibility in inter-temporal choice. Front Aging Neurosci. 2015 Mar 27;7:41.

Regier PS, Redish, AD. Posterior dorsomedial striatum represents a strategy change, and dorsolateral striatum represents habit on the Hebb-Williams maze. In preparation for Journal of Neurophysiology. 2015

Regier PS, Redish AD. Implications of the multiple-decision making systems theory for Contingency Management. Under review at Psych Review. 2015

AM Wikenheiser, Redish AD. (2015). Hippocampal sequences and the cognitive map. In: Analysis and Modeling of Coordinated Multi-neuronal Activity Springer New York, 105-129.

AM Wikenheiser, Redish AD, Hippocampal theta sequences reflect current goals. Nature Neuroscience Wikenheiser AM, Redish AD. Nat Neurosci. 2015 Feb;18(2):289-94.

Hills TT, Todd PM, Lazer D, Redish AD, Couzin ID; Cognitive Search Research Group. Exploration versus exploitation in space, mind, and society. Trends Cogn Sci. 2015 Jan;19(1):46-54.

Redish AD, Mizumori SJ. Memory and decision making. Neurobiol Learn Mem. 2015 Jan;117:1-3.

Powell, N. J. and Redish, A. D. Complex neural codes in rat prelimbic cortex are stable across days on a spatial decision task. Frontiers in Behavioral Neuroscience. 2014 Apr 23;8:120.

Stott JJ, Redish AD. A functional difference in information processing between orbitofrontal cortex and ventral striatum during decision-making behaviour. Philos Trans R Soc Lond B Biol Sci. 2014 Nov 5;369(1655).

Wikenheiser AM, Redish AD. Decoding the cognitive map: ensemble hippocampal sequences and decision making. Curr Opin Neurobiol. 2014 Oct 17;32C:8-15.

Steiner AP, Redish AD. Behavioral and neurophysiological correlates of regret in rat decision-making on a neuroeconomic task. Nat Neurosci. 2014 Jul;17(7):995-1002.

A. P. Steiner, A. D. Redish (2012) “The road not taken: neural correlates of decision making in orbitofrontal cortex” Frontiers in Decision Neuroscience 6:131 doi:10.3389/fnins.2012.00131.

M. A. A. van der Meer, Z. Kurth-Nelson, A. D. Redish (2012) “Information processing in decision-making systems” The Neuroscientist 18(4):342-359.

A.E. Papale, J. J. Stott, N. J. Powell, P. S. Regier, A. D. Redish
(2012) “Interactions between Deliberation and Delay-Discounting in Rats” Cognitive, Affective, and Behavioral Neuroscience 12(3):513-526.

A.S. Gupta, M.A.A. van der Meer, D.S.Touretzky, A.D. Redish (2012) “Segmentation of spatial experience by hippocampal theta sequences”
Nature Neuroscience 15(1032-1039).

J. E. Ferguson, A. D. Redish (2011) “Wireless communication with implanted medical devices using the conductive properties of the body”
Expert Reviews of Medical Devices 8(4):427-33.

M. A. A. van der Meer, A. Johnson, N. C. Schmitzer-Torbert, A. D.
(2010) “Triple dissociation of information processing in dorsal striatum, ventral striatum, and hippocampus on a learned spatial decision task” Neuron.67:25-32.

A. S. Gupta, M. A. A. van der Meer, D. S. Touretzky, A. D. Redish
(2010) “Hippocampal replay is not a simple function of experience”
Neuron 65(5):695-705.

A. Johnson, A. Fenton, C. Kentros, A. D. Redish (2009) “Looking for cognition in the structure in the noise” Trends in Cognitive Sciences 13(2):55-64.

A. D. Redish, S. Jensen, A. Johnson (2008) “A unified framework for
addiction: vulnerabilities in the decision process” Behavioral and Brain Sciences 31:415-437 with discussion pp. 437-487.

A. Johnson, A. D. Redish (2007) “Neural ensembles in CA3 transiently encode paths forward of the animal at a decision point” Journal of Neuroscience 27(45):12176-12189 J. C. Jackson, A. D. Redish (2007) “Network dynamics of hippocampal cell-assemblies resemble multiple spatial maps within single tasks”
Hippocampus 17:1209-1229.


A. D. Redish. "Beyond the Cogntive Map: From Place Cells to Episodic Memory" (MIT Press) 1999.

Current Graduate Students:

Andrew Papale (Neuroscience, University of Minnesota).

Paul Regier (Neuroscience, University of Minnesota).

Andrew Steiner (Neuroscience, University of Minnesota).

Jeff Stott (Neuroscience, University of Minnesota).

Nate Powell (Neuroscience, University of Minnesota).

Andrew Wikenheiser (Neuroscience, University of Minnesota).

Former Graduate Students:

Adam Johnson (Ph.D. 2008, Neuroscience, University of Minnesota).

Jadin Jackson (Ph.D. 2006, Neuroscience, University of Minnesota).

Neil Schmitzer-Torbert (Ph.D. 2004, Neuroscience, University of Minnesota).