LiLian Yuan, Ph.D.
Assistant Professor, Department of Neuroscience
Synaptic organization, connectivity and persistent activity in the prefrontal cortex
Signaling propagation and integration in neuronal dendrites
Alcohol intoxication and dependence
(For a comprehensive list of recent publications, refer to PubMed, a service provided by the National Library of Medicine.)
Lockridge A, B Newland, S Printen, LL Yuan (2013). Head movement is an independent and serotonergically mediated behavior in the mouse forced swim and tail suspension tests. In press. Behavioral Brain Research.
Meehan AL, X Yang, LL Yuan, SM Rothman (2012). Levetiracetam has an activity-dependent effect on inhibitory transmission. Epilepsia. 53(3): 469-76
Lockridge A, G Romero, J Harrington, Z Gong, B Newland, A Cameron, LL Yuan (2012). Timing-dependent reduction in ethanol sedation and drinking preference by NMDA receptor co-agonist D-serine. Alcohol. 46(4): 389-400.
Parent M, Yuan LL. Automated detection and analysis of neuronal persistent activity. J Neurosci Methods. 2011 Oct 15;201(2):361-7. Epub 2011 Aug 25.
Meehan AL, X Yang, B McAdams, LL Yuan, SM. Rothman (2011). A New Mechanism for Antiepileptic Drug Action: Vesicular Entry May Mediate the Effects of Levetiracetam. J. Neurophys. doi: 10. 1152/ jn. 00279. 2011
Kong F, J Zhu, J Wu, J Peng, Y Wang, Q Wang, S Fu, LL Yuan, T Li (2011). dbCRID: A Database of Chromosomal Rearrangements in Human Diseases. Nucleic Acids Res 39: D895-900
Hoover B, M Reed, J Su, L Kotilinek, R Penrod, GA Carlson, L Lanier, LL Yuan, K Ashe, D Liao (2010). Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron, 68: 1067-81
Lockridge A, LL Yuan (2010). Spatial learning deficits in mice lacking the Kv4.2 subunit. Hippocampus, DOI: 10.1002/hipo.20877
Lockridge A, J Su, LL Yuan (2010). Abnormal 5-HT modulation of stress behaviors in the Kv4.2 knockout mice. Neuroscience, 170:1086-1097
Zhao C, L Wang, T Netoff, LL Yuan (2010). Dendritic mechanisms controlling the threshold and timing requirement of synaptic plasticity. Hippocampus. DOI: 10.1002/hipo.20748
Parent M, L Wang, J Su, T Netoff, LL Yuan (2010). Identification of the hippocampal input to medial prefrontal cortex in vitro. Cerebral Cortex 20: 393-403
Wang L, LL Yuan (2009). Activation of muscarinic acetylcholine receptors leads to long-term depression of the hippocampal-mPFC pathway. J. Physiol. 587: 5139-5147
Yuan LL, X Chen (2006). Diversity of potassium channels in neuronal dendrites. Prog. in Neurobiol. 8: 374-89
Chen X*, LL Yuan*, C Zhao, S Birnbaum, A Frick, WE Jung, TL Schwarz, JD Sweatt, D Johnston (2006). ( * Co-first authors) Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. J. Neurosci. 26: 12143-12151.
Former Graduate Students:
Marc Parent (Ph.D. 2010, Neuroscience, University of Minnesota).