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Undergraduate Institution and Major/Degree:
Major Advisor(s):
Research Description:
My current interests include the ability of Multipotent Adult Progenitor Cells from bone marrow to generate neurons in vitro and in vivo, and their behavior in a mouse model of stroke. Although neural differentiation of bone marrow-derived cells is highly controversial, preliminary evidence suggests that MAPCs have certain properties of embryonic stem cells, and may be capable of neural differentiation, though further work is needed to confirm this. In the injured brain, MAPCs migrate robustly toward areas of ischemia where they proliferate to replace the infarct area. The functional implications and mechanisms of this behavior are under investigation. Additional interests include the behavior of endogenous neural stem cells, and the potential to mobilize these for treatment of CNS injury or degeneration.
Conferences Attended and Presentations:
- Society for Neuroscience: 2003, 2005
- American Society for Nuerochemistry, Madison, WI, June 28, 2005
Selected Publications and Presentations:
Publications:
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Terry C. Burns, Xilma R. Ortiz-González, María Gutiérrez-Pérez, C. Dirk Keene, Rohit Sharda, Zachary L. Demorest, Yuehua Jiang, Molly Nelson-Holte, Mario Soriano, Yasushi Nakagawa, María Rosario Luquin, Jose Manuel Garcia Verdugo, Felipe Prósper, Walter C. Low, Catherine M. Verfaillie Thymidine Analogs are Transferred from Pre-Labeled Donor to Host Cells in the Central Nervous System after Transplantation: A Word of Caution. Stem Cells. 2006 Apr;24(4):1121-7
• Commentary: Pearson H. Stem-Cell tagging shows flaws. Nature. 2006 Feb 2;439(7076):519
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Marta Serafini, Scott J. Dylla, Masayuki Oki, Yves Heremans, Yuehua Jiang, Shannon M. Buckley, Beatriz Pelacho, Terry Burns, Sarah Frommer, Derrick J. Rossi, David Bryder, Angela Panoskaltsis-Mortari, Matthew J. O'Shaughnessy, Molly Nelson-Holte, Irving L. Weissman, Bruce R. Blazar and Catherine M.Verfaillie Complete Lymphohematopoietic Reconstitution by Multipotent Adult Progenitor Cells J. Experimental Medicine 2006 (In press)
Abstracts:
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Terry C. Burns, Xilma R. Ortiz-González, C. Dirk Keene, Zachary L. Demorest, Yuehua Jiang, Yasushi Nakagawa, Catherine M.Verfaillie, Walter C. Low. BrdU is Not a Reliable Label for Transplanted Cells in the Embryonic and Neonatal Host Brain. Society for Neuroscience, 2005
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Katherine E. Himes, Terry Burns, Virginia S. Seybold, William C. Engeland. Experience of a neuroscience doctoral program as partner program in the Carnegie Initiative on the Doctorate. Society for Neuroscience, 2005
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Terry Burns, Catherine Verfaillie, Walter Low, Yuehua Jiang. Multipotent Adult Progenitor Cells (Invited Speaker). American Society for Nuerochemistry, Madison, WI, June 28, 2005.
Awards and Honors:
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Selected to participate in Route28 summit in neurobiology, Germany (2007)
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Doctoral Dissertation Fellowship, University of Minnesota (2006-2007)
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American Society for Neural Therapy and Repair Travel Award (2006)
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Hough Parkinson's Grant Recipient - $63,000 (2005-2006)
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Society For Neuroscience Predoctoral Travel Award (2005)
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BMEI Tissue Engineering Fellowship (2004-2005)
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Smithberg Memorial Prize for outstanding achievement in neuroscience (2004)
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Chancellor's List (Who's Who Among Graduate Students; 2004, 2005)
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3M Science and Technology fellowhip (2003-2007)
Home Town:
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