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Laura Stone Ph.D. 1999 Thesis Title: Alpha-2 Adrenergic Receptor Subtypes in Pain and Analgesia Advisors: Robert Elde and George Wilcox

Honors:

1998, Patrick J Manning Research Award
1999, Bacaner Research Award in Basic Medical Science
2006, American Pain Society John C. Liebeskind Early Career Scholar Award

Thesis Publications:

Stone LS, Vulchanova L, Riedl MS, Wang J, Williams FG, Wilcox GL, Elde R. (1999) Effects of peripheral nerve injury on alpha-2A and alpha-2C adrenergic receptor immunoreactivity in the rat spinal cord. Neuroscience 93:1399-1407.

Stone LS, Broberger C, Vulchanova L, Wilcox GL, Hokfelt T, Riedl MS, Elde R. (1998) Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord. J Neurosci 18:5928-5937.

Stone LS, MacMillan LB, Kitto KF, Limbird LE, Wilcox GL. (1997) The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy. J Neurosci 17:7157-7165.

Recent Publications:

In press C.A. Fairbanks, K.F. Kitto, H.O. Nguyen, L.S. Stone, and G.L. Wilcox. Clonidine and Dexmedetomidine Produce Antinociceptive Synergy in Mouse Spinal Cord. Anesthesiology.

2007 L.S. Stone , K.F. Kitto, J.C. Eisenach , C.A. Fairbanks and G.L. Wilcox. ST91 [ 2-(2,6-Diethylphenylamino)-2-imidazoline Hydrochloride] - Mediated Spinal Antinociception and Synergy with Opioids Persists in the Absence of Functional Alpha-2A- or Alpha-2C- Adrenergic Receptors. Journal of Pharmacology and Experimental Therapeutics 323(3):899-906 2007.

2007 C.J. Goracke-Postle, A.C. Overland , M.A. Riedl, L.S. Stone and C.A. Fairbanks . Potassium- and capsaicin-induced release of agmatine from spinal nerve terminals. Journal of Neurochemistry 102:1738-1748; 2007.

2007 C.J. Goracke-Postle, A.C. Overland , L.S. Stone and C.A. Fairbanks . A polyamine transport system mediates uptake of tritiated agmatine into spinal nerve terminals. Journal of Neurochemistry 100:132-141; 2007.

2007 T. Ness, U. Wesselmann, L. Stone, P. Mantyh, J. Neubert. The American Pain Society and Translational Pain Research: A Position Statement from the American Pain Society. Copyright 2007 by the American Pain Society.