Clinical and Research Interests:
Dr. Fatemi is the Associate Chair for Neuroscience and Translational Research for the Department of Psychiatry; the Bernstein Endowed Chair in Adult Psychiatry; Professor of Psychiatry, Neuroscience and Pharmacology, at the University of Minnesota Medical School. Dr. Fatemi’s research interests include the molecular causes and the biological basis of neurodevelopmental disorders, primarily schizophrenia and autism. His clinical interests include treatment and psychopharmacology of major depression, bipolar disorder, and schizophrenia. He has over 15 years experience in the treatment of psychiatric disorders. Dr. Fatemi is a member of the American College of Psychiatrists, a Fellow the American College of Neuropsychopharmacology, and the International College of Neuropsychopharmacology, and a Distinguished Fellow of the American Psychiatric Association.
(For a comprehensive list of recent publications, refer to PubMed, a service provided by the National Library of Medicine.)
- Folsom TD, Higgins L, Markowski TW, Griffin TJ, Fatemi SH. Quantitative proteomics of forebrain subcellular fractions in fragile X mental retardation 1 knockout mice following acute treatment with 2-Methyl-6-(phenylethynyl)pyridine: Relevance to developmental study of schizophrenia. Synapse. 2019 Jan;73(1):e22069.
- Fatemi SH, Wong DF, Brašić JR, Kuwabara H, Mathur A, Folsom TD, Jacob S, Realmuto GM, Pardo JV, Lee S. Metabotropic glutamate receptor 5 tracer [18F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study. Cerebellum Ataxias. 2018 Feb 12;5:3.
- Fatemi SH, Folsom TD, Thuras PD. Altered subcellular localization of fragile X mental retardation signaling partners and targets in superior frontal cortex of individuals with schizophrenia. Neuroreport. 2017;28:1066-1070.
- Fatemi SH, Folsom TD, Thuras PD. GABAA and GABAB receptor dysregulation in superior frontal cortex of subjects with schizophrenia and bipolar disorder. Synapse. 2017;71(7). doi: 10.1002/syn.21973.
- Fatemi SH, Folsom TD, Liesch SB, Kneeland RE, Karkhane Yousefi M, Thuras PD. The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum. J Neurosci Res. 2017;95(5):1110-1122.
- Frye RE, Casanova MF, Fatemi SH, Folsom TD, Reutiman TJ, Brown GL, Edelson SM, Slattery JC, Adams JB. Neuropathological mechanisms of seizures in autism spectrum disorder. Front Neurosci. 2016 May 10;10:192.
- Folsom TD, Thuras PD, Fatemi SH. Protein expression of targets of the FMRP regulon is altered in brains of subjects with schizophrenia and mood disorders. Schizophr Res. 2015;165:201-211.
- Fatemi SH, Folsom TD. GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism. SSchizophr Res. 2015;167:42-56..
- Fatemi SH, Folsom TD. Existence of monomer and dimer forms of mGluR5, under reducing conditions in studies of postmortem brain in various psychiatric disorders. Schizophr Res. 2014;158:270-271.
- Fatemi SH, Reutiman TJ, Folsom TD, Rustan OG, Rooney RJ, Thuras PD. Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism. J Autism Dev Disord. 2014;44:1833-1845.