Figure 1. Neurogenesis persists in adult mammals throughout life. a: The parasagittal section of a mouse brain demonstrates the brain regions involved in rodent adult neurogenesis (red). b,c: Coronal sections at the approximate regions of the dashed lines. b: The SVZ, where neural stem cells persist throughout life. Slowly dividing type B cells give rise to rapidly dividing type C cells, which in turn give rise to migratory neuroblasts. These reach the olfactory bulb via the rostral migratory stream (RMS), and there differentiate into granule and periglomerular neurons. c: The dentate gyrus, where new neurons are also born throughout life. Type B cells in the subgranular zone (SGZ) give rise to precursor cells, which migrate up the radial projection of type B cells to become granule neurons in the granular zone (GZ). Parasagittal and coronal brain slice images were adapted from Paxinos and Franklin ([ 2004 ]). The subventricular zone diagram in b illustrates principles from Doetsch ([ 2003 ]). For abbreviations , see list.