Balvindar Singh

Entering Class - 2014

Member of MSTP (MD/PhD) program

E-MAIL: singh308@umn.edu

Undergraduate Instutition And Major:
University of California, San Diego. Microbiology. 2011

Graduate Advisor:
Michael Lee, Ph.D., Department of Neuroscience

Thesis Committee Members:

Description Of Graduate Research:
Parkinson’s disease (PD), the second most common neurodegenerative disease, is characterized by intracellular inclusions called Lewy bodies, and loss of selective brain regions at the neuronal level, resulting in overt motor abnormalities at the clinical level. However, the neuropathology observed in PD extends beyond these selective regions implicated as the source these motor deficits, and thus a majority of PD patients develop other symptoms such as dementia. To that end, understanding the mechanism by which α-synulcein, a major component of Lewy bodies and protein mutated in genetic versions of PD, contributes to cognitive deficits will enhance our knowledge of the disease process and identify new targets for therapeutic intervention.

Graduate Level Publication(s):

Teravskis PJ, Covelo A, Miller EC, Singh B, Martell-Martínez HA, Benneyworth MA, Gallardo C, Oxnard BR, Araque A, Lee MK, Liao D. A53T mutant alpha-synuclein induces tau dependent postsynaptic impairment independent of neurodegenerative changes. J Neurosci. 2018;38:9754-9767.

Research Categories:

  • Neurodegenerative Diseases & Neural Injury
  • Synaptic Plasticity & Learning
  • Regenerative Medicine for Neural Systems

Rotations:

GPN Committees:
Student Board First Year Representative 2014-2015.

Why Did You Choose MN?
The MD/PhD program at the U of MN is strong. There are many good clinical opportunities and medical and graduate training. During the interview process, students seemed happy and cohesive and the faculty seemed involved and invested.

Student Mentor And The Best Advice They Gave.
Jenny Zick: Don't let people tell you what to do when picking an advisor.

Balvindar Singh