Mariah Wu

Entering Class - 2015

E-MAIL: mmwu@umn.edu

Undergraduate Institution And Major:
University of Illinois at Urbana-Champaign, B.S., Molecular & Cellular Biology and Psychology, 2015

Graduate Advisor: 
Stanley Thayer, Ph.D., Department of Pharmacology

Thesis Committee Members: 

Description Of Graduate Research: 
Our lab is interested in how HIV neurotoxins and cannabinoids affect synaptic plasticity. We are interested in the endocannabinoid system because it provides on-demand endogenous neuroprotection against excitotoxic insults. My research aims to examine modulation of this system following exposure to HIV Tat and gp120. I use optical imaging and electrophysiological techniques on primary hippocampal cultures to determine the effects of these neurotoxins on CB1 signaling, and endogenous cannabinoid tone. 

Research Categories: 

  • Neurodegenerative Diseases & Neural Injury
  • Synaptic Plasticity & Learning

Graduate Level Awards And Honors:

  • NIDA PharmacoNeuroImmunology (PNI) training program, 2017

Graduate Level Publications:

Green MV, Raybuck JD, Zhang X, Wu MM, Thayer SA. Scaling Synapses in the Presence of HIV.  Neurochem Res. 2018 Mar 14;. [Epub ahead of print]  PMID: 29541929

Graduate Level Abstracts:

  • Wu MM, Thayer SA. Prolonged exposure to HIV-1 Tat modulates the endocannabinoid system. Abstract for poster presentation, Graduate Program in Neuroscience Annual Retreat 2017, University of Minnesota, Minneapolis, MN.

Rotations: 

Why Did You Choose MN?
The faculty here are conducting top-tier research, especially in the field of neurodegenerative disease. Additionally, the sense of camaraderie among of fellow graduate students and faculty is incomparable to any other program I have experienced.

Wu 2017