The role of actin-binding proteins in mediating growth cone guidance to
Associate Director and Research Scientist with ScienCell Research Laboratories
Undergraduate Institution and Major/Degree:
State University of New York (SUNY) College at Geneseo; BA in psychology; 2004
Paul Letourneau, Ph.D.
I'm interested in how neural networks are formed during development and how to repair damaged networks in adulthood – as in the case of spinal cord injury. Specifically, I'm interested in how the motile tips of extending axons - growth cones - respond to the myriad of extracellular molecular cues that result in their connection with the correct target. We use in vitro as well as in vivo techniques to study the roles of specific proteins in this process.
- Lorene Lanier
- Lance Zirpel
- Paul Letourneau
- Society for Neuroscience, Annual Meeting: 2002-2007
- Marsick BM, San Miguel-Ruiz JE, Letourneau PC. Activation of ezrin/radixin/moesin mediates attractive growth cone guidance through regulation of growth cone actin and adhesion receptors. J Neurosci. 2012 Jan 4;32(1):282-96.
- Roche FK, Marsick BM, Letourneau PC. (2009). Protein synthesis in distal axons is not required for growth cone responses to guidance cues. J Neurosci. 2009 Jan 21;29(3):638-52.
Awards and Honors:
- Stark Travel Award; to learn a technique with Jim Bamburg at Colorado State University , 2007.
- Buffalo , NY