Eric Miller

Ph.D. - 2013


Thesis Title:

AMPA Glutamate Receptor Trafficking in Models of Disease

Current Position:

Postdoctoral Fellow, The University of Alabama at Birmingham

Undergraduate Institution and Major/Degree:

B.A., Psychology and Political Science, 2008, Gustavus Adolphus College, MN

Current Position:

Postdoctoral Fellow, The University of Alabama at Birmingham

Major Advisor(s):

Dezhi Liao, M.D., Ph.D.

Research Description:

The role of functional and structural plasticity of dendritic spines in drug addiction has recently attracted great attention from both basic researchers and clinicians. Although it is known that drugs of abuse cause spine plasticity, the intracellular signaling pathway through which these changes are mediated is unknown. My thesis research aims to reveal a novel signaling pathway that mediates drug-induced plasticity of dendritic spines. Therefore, the CaMKII/Kalirin7/Rac1 signaling pathway may become a therapeutic target for the prevention and treatment of drug addiction.

Lab Rotations:

  • Mark Thomas
  • Dezhi Liao
  • Bob Meisel

Conferences Attended:

  • Society for Neuroscience - 2007, 2008, 2009, 2010 and 2012
  • International Brain Research Meeting - 2011

Committee Members:

  • Bob Meisel - Chair
  • Paulo Kofuji
  • Stanley Thayer
  • Dezhi Liao - Advisor

Selected Publications and Presentations:

Liao D, Miller EC, Teravskis PJ. Tau acts as a mediator for Alzheimer's disease-related synaptic deficits. Eur J Neurosci. 2014 Apr;39(7):1202-13.

Miller EC, Teravskis PJ, Dummer BW, Zhao X, Huganir RL, Liao D. Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits. Eur J Neurosci. 2014 Apr;39(7):1214-24.

Miller E.C., Zhang, L., Dummer, B.W., Cariveau, D.R. Loh, H., Law, P.Y., Liao, D. (2011) Differential modulation of drug-induced structural and functional plasticity of dendritic spines. Molecular Pharmacology 82:333-43. PMCID: PMC3400837

Professional Memberships:

  • Society for Neuroscience

Home Town:

  • Racine, WI
Eric Miller