Marija Cvetanovic, Ph.D.

Assistant Professor, Neuroscience

E-MAIL: mcvetano@umn.edu


Research Interests:

Our lab aims to understand how different brain cells and their interactions influence the onset and progression of neurodegenerative diseases. The ultimate goal is to increase knowledge of these disorders and open new avenues for therapeutic approaches.


Selected Publications:

(For a comprehensive list of recent publications, refer to PubMed, a service provided by the National Library of Medicine.)

  • Qu W, Johnson A, Kim JH, Lukowicz A, Svedberg D, Cvetanovic M. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice. J Neuroinflammation. 2017;14(1):107.
  • Cvetanovic M, Hu YS, Opal P. Mutant ataxin-1 inhibits neural progenitor cell proliferation in SCA1. Cerebellum. 2017;16:340-347.
  • Stanojlovic M, Pang X, Lin Y, Stone S, Cvetanovic M, Lin W. Inhibition of vascular endothelial growth factor receptor 2 exacerbates loss of lower motor neurons and axons during experimental autoimmune encephalomyelitis. PLoS One. 2016;11(7):e0160158.
  • Asher M, Johnson A, Zecevic B, Pease D, Cvetanovic M. Ataxin-1 regulates proliferation of hippocampal neural precursors. Neuroscience. 2016;322:54-65.
  • Cvetanovic M, Ingram M, Orr H, Opal P. Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1. Neuroscience. 2015;289:289-299.
  • Cvetanovic M. Decreased expression of glutamate transporter GLAST in bergmann glia is associated with the loss of Purkinje neurons in the spinocerebellar ataxia type 1.Cerebellum. 2015;14:8-11.
  • Venkatraman A, Hu YS, Didonna A, Cvetanovic M, Krbanjevic A, Bilesimo P, Opal P. The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1. Hum Mol Genet. 2014;23:3733-3745.
  • Cvetanovic M, Kular RK, Opal P. LANP, an inhibitor of histone acetyl transferase (INHAT) plays a role in Spinocerebellar ataxia 1. Neurobiol Dis. 2012;48:526-532.
  • Cvetanovic M, Patel J, Kini A, Hugo V, Opal P. VEGF ameliorates the ataxic phenotype in spinocerebellar ataxia 1 (SCA1) mice” Nature Med. 2011;17:1445-1447.

Current Graduate Students:

 

Former Graduate Students:

Melissa Asher (Masters, University of Minnesota)

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