Ann Parsons

Ph.D. 1996

Thesis Title:

Spinal Neurokinin and Calcitonin Gene-Related Peptide Receptors and their Role in Hyperalgesia

Current Position:

Professor, Department of Biology, University of Wisconsin - Stout

Major Advisor(s):

Virginia Seybold, Ph.D.

Selected Publications:

  • Christopoulos A, Parsons AM, El-Fakahany EE. Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor. J Pharmacol Exp Ther. 1999;289(3):1220-8.
  • Parsons AM, Sorman JL, El-Fakahany EE. Regulation of M1 muscarinic receptor-mediated signaling in intact cells by exogenous, but not endogenously produced, nitric oxide. Neurochem Res. 1999;24(1):85-94.
  • Christopoulos A, Parsons AM, Lew MJ, El-Fakahany EE. The assessment of antagonist potency under conditions of transient response kinetics. Eur J Pharmacol. 1999;382:217-227.
  • Wotta DR , Parsons AM, Hu J, Grande AW, El-Fakahany EE. M1 muscarinic receptors stimulate rapid and prolonged phases of neuronal nitric oxide synthase activity: involvement of different calcium pools. J Neurochem. 1998;71(2):487-97.
  • Parsons AM, Seybold VS. Calcitonin gene-related peptide induces the formation of second messengers in primary cultures of neonatal rat spinal cord. Synapse. 1997;26(3):235-42.
  • Wang SZ, Lee SY, Zhu SZ, Wotta DR, Parsons AM, el-Fakahany EE. Activation of neuronal nitric oxide synthase by M2 muscarinic receptors associated with a small increase in intracellular calcium. Pharmacology. 1997;55(1):10-17.
  • Parsons AM, Honda CN, Jia YP, Budai D, Xu XJ, Wiesenfeld-Hallin Z, Seybold VS. Spinal NK1 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation. Brain Res. 1996;739(1-2):263-75.
  • Parsons AM, el-Fakahany EE, Seybold VS. Tachykinins alter inositol phosphate formation, but not cyclic AMP levels, in primary cultures of neonatal rat spinal neurons through activation of neurokinin receptors. Neuroscience. 1995;68(3):855-65.
  • Parsons AM, Seybold VS, Chandan R, Vogt J, Larson AA, Murray CR, Soldani G, Brown DR. Neurokinin receptors and mucosal ion transport in porcine jejunum. J Pharmacol Exp Ther. 1992;261(3):1213-21.
  • Seybold VS, Parsons AM, Aanonsen LM, Brown DR. Characterization and autoradiographic localization of gastrin releasing peptide receptors in the porcine gut. Peptides. 1990;11(4):779-87.
Ann Parsons