Gunner Drossel

PhD 2024

Pronouns: he/him

PhD Thesis

Addressing Individual Heterogeneity in the Neurobehavioral Factors Related to Substance Use Disorders

Current Position:

MedTech Strategy PhD-Consultant at IQVIA

Undergraduate Institution and Major:

Hamline University, B.S. in Biology and B.A. in Psychology, 2017

Graduate Advisor:

Anna Zilverstand, Ph.D., Department of Psychiatry & Behavioral Sciences

Graduate Research:

I study the individual heterogeneity of substance use disorders using a multimodal approach that combines behavioral data with functional MRI data. I also investigate ways in which preclinical models of functional neuroimaging with drug administration inform human subjects research on drug addiction and vice-versa. The whole of my research helps to inform future development of substance use disorder treatments.

Graduate Publications:

  • Drossel G, Heilbronner SR, Zimmermann J, Zilverstand A. Neuroimaging of the effects of drug exposure or self-administration in rodents: A systematic review. Neurosci Biobehav Rev. 2024 Aug 1;164:105823. 
  • Drossel G, Zilverstand A. Towards personalized medicine: subtyping using functional profiles. Neuropsychopharmacology. 2024 Jan;49(1):347-348.
  • Drossel G, Brucar LR, Rawls E, Hendrickson TJ, Zilverstand A. Subtypes in addiction and their neurobehavioral profiles across three functional domains. Translational Psychiatry, 2023;13(1):127. 
  • Niklason GR, Rawls E, Ma S, Kummerfeld E, Maxwell AM, Brucar LR, Drossel G, Zilverstand A. Explainable machine learning analysis reveals gender differences in the phenotypic and neurobiological markers of cannabis use disorder. Sci Rep. 2022 Sep 17;12(1):15624.

Graduate Presentations

  • Drossel, G., Brucar, L., Rawls, E., Zilverstand, A., “An Empirically Derived Three‐Domain Model of Substance Use Disorder”, Society for Biological Psychiatry Annual Meeting, Virtual, 2021 
  • Drossel, G., Zimmermann, J., Thomas, M., Zilverstand, A., “Chronic Opioid Self‐Administration and Neuroimaging in Rodents: Establishing a Translational Addiction Connectome”, University of Minnesota Graduate Program in Neuroscience Annual Retreat, Minneapolis, MN, 2021 
  • Drossel, G., Brucar, L., Rawls, E., Zilverstand, A., “Subtypes in Addiction and Their Neurobehavioral Impairments in Approach Behavior, Negative Emotionality and Executive Function”, Society for Neuroscience, Virtual, 2021
  •  Drossel, G., Angeles-Valdez, D., Garza-Villarreal, E., Zilverstand, A., “Subtypes in Individuals With Current Cocaine Use Disorder and Their Impairments in Negative Emotionality and Executive Function”, Society for Biological Psychiatry Annual Meeting, New Orleans, LA, 2022 
  • Drossel, G., Zimmermann, J., Zilverstand A., “Functional neuroimaging of the effects of drug exposure or self-administration in rodents: A systematic review”, Society for Neuroscience, San Diego, CA, 2022 
  • Drossel, G., Maxwell, A., Kondepudy, M., Zilverstand, A., “Effects of Alcohol Use and Race on Drug Cue Reactivity”, University of Minnesota Graduate Program in Neuroscience Annual Retreat, Minneapolis, MN, 2024

Graduate Awards/Honors

  • 2023-24 Doctoral Dissertation Fellowship, Graduate School, University of Minnesota
  • 2023 American Legion Brain Science Award, University of Minnesota and Minneapolis VA Medical Center
  • 2023 Invited Speaker, Graduate Program in Neuroscience Annual Retreat, University of Minnesota
  • 2020-23 T32 Training Grant in Drug Addiction, National Institute on Drug Abuse (5T32DA007234-29)
  • 2022 Poster Award, Office of Biomedical Graduate Research, Research Recognition Day, University of Minnesota,
  • 2019-20 T32 Predoctoral Training Grant, National Institute of Neurological Disorders and Stroke (T32NS105604-04)

GPN Committees

Retreat Planning Committee 2021-2022
Career Facilitation Committee 2021-Present

Thesis Committee

Benjamin Saunders, Ph.D., Department of Neuroscience (Chair)
Anna Zilverstand, Ph.D., Department of Psychiatry & Behavioral Sciences (Advisor)
Jan Zimmermann, Ph.D., Department of Neuroscience
Katie Cullen, M.D., Department of Psychiatry & Behavioral Sciences

Rotations

Jocelyn Richard, Ph.D., Department of Neuroscience 
Anna Zilverstand, Ph.D., Department of Psychiatry & Behavioral Sciences 
Sophia Vinogradov, M.D., Department of Psychiatry & Behavioral Sciences
Katie Cullen, M.D., Department of Psychiatry & Behavioral Sciences

Undergraduate Research

Undergraduate Research: Assessing the effect of heavy metal concentrations on antibiotic resistance genes in soil bacteria 

Postbac Research: Researching cellular signaling of neuropeptide GPCRs related to control of stress-responsive gene transcription

Why did you choose Minnesota?

I was born and raised in Minnesota and went to college at Hamline University in St. Paul, MN. After two years working as a postbac researcher at the National Institutes of Health in Bethesda, MD, I decided I was ready to return to Minnesota to be close to friends and family.

Picture of Gunner Drossel