Brianna Dailey-Krempel

Entering Class - 2021

Pronouns: she/her

E-MAIL:  [email protected]

Undergraduate Institution and Major:

University of Nevada-Reno, B.S. in Neuroscience, 2020

Graduate Advisor

Lucy Vulchanova, Ph.D., Department of Neuroscience
John Osborn, Ph.D., Department of Surgery

Graduate Research:

My thesis research focuses on the role of renal afferent (sensory) nerves in the development and maintenance of a salt-induced model of hypertension. I use adeno-associated viruses to trace renal afferents within the renal cortex and renal pelvis to identify where these afferents terminate centrally in the spinal cord and caudal brainstem. Using the deoxycorticosterone-acetate (DOCA)-salt mouse model of hypertension, I am investigating which central autonomic blood pressure regulating regions are activated at two time points of hypertension development and maintenance, and using renal afferent denervation to see which regions may be modulated by renal afferent input.

Graduate Publications

  • Evans LC, Dailey-Krempel B, Lauar MR, Dayton A, Vulchanova L, Osborn JW. Renal interoception in health and disease. Auton Neurosci. 2024 Jul 31;255:103208. 
  • Dailey-Krempel B, Martin A, Jo H-N, Junge H, Chen Z. A tug-of-war between DCC and ROBO1 signaling during commissural axon guidance. Cell Rep. 2023 May 30;42(5):112455.

Graduate Presentations

Renal Afferent Input to Central Autonomic Blood Pressure Centers. Graduate Program in Neuroscience Colloquium Series, November 2024.

Graduate Awards/Honors

Sping and Ying Ngoh Lin Award 2023 NIH NINDS T32 Grant Appointee 2021-2022

GPN Committees

GPN Admissions Committee, 2023-present
GPN Student Board, 2023-present

Thesis Committee

Catherine Kotz, Ph.D., Departments of Geriatric Research, Education and Clinical Care (GRECC); Food Science and Nutrition; MN Obesity Center (Chair)
Lucy Vulchavnova, Ph.D., Department of Neuroscience (Co-Advisor)
John Osborn, Ph.D., Department of Surgery (Co-Advisor) 
Louise Evans, Ph.D., Department of Surgery 
Zhe Chen, Ph.D., Department of Neuroscience

Rotations

Alfonso Araque, Ph.D. & Paulo Kofuji, Ph.D., Department of Neuroscience
Zhe Chen, Ph.D., Department of Neuroscience
Lucy Vulchanova, Ph.D., Department of Neuroscience & John Osborn, Ph.D., Department of Surgery
Catherine Kotz, Ph.D., Departments of Geriatric Research, Education and Clinical Care (GRECC); Food Science and Nutrition; MN Obesity Center

Undergraduate Research

During undergrad, I was involved in a project investigating the role of GABA and insulin receptors in olfactory sensory neurons in the feeding behavior of Drosophila larvae.

Undergraduate Publications

  • Slankster E, Kollala S, Baria D, Dailey-Krempel B, Jain R, Odell S, and Mathew D. Mechanism underlying starvation-dependent modulation of olfactory behavior in Drosophila larva. Scientific Reports. 2020 Feb. 10:3119. doi: 10.1038/s41598-020-60098-z.

Undergraduate Awards/Honors

Nevada Undergraduate Research Award 2020

Dailey-Krempel