Entering Class 2020
Member of MSTP (MD/PhD) program
E-MAIL: brow4200@umn.edu
Undergraduate Institution and Major:
Villanova University, B.S. in Biochemistry and Neuroscience, 2018
Graduate Advisor:
Rocio Gomez Pastor, Ph.D., Department of Neuroscience
Graduate Publications:
- Striatal spatial heterogeneity, clustering, and white matter association of GFAP+ astrocytes in a mouse model of Huntington's disease. Front Cell Neurosci. 2023 Apr 28;17:1094503.
- Yu D, Zarate N, Cuccu F, Yue JS, Brown TG, Tsai A, Mansky R, Jiang K, Kim H, Nanclares C, Nichols-Meade T, Larson SN, Gundry K, Zhang Z, Benneyworth M, Öz G, Cvetanovic M, Araque A, Gomez Pastor R. CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease. Acta Neuropathol Commun 2022;10:83.
Graduate Presentations:
Oral Presentation:
- Brown TG, Thayer, M, Gomez-Pastor, R. Striatal compartmentalization and clustering of different subtypes of astrocytes is altered in Huntington’s disease. Expanded Repeats conference. June 17-18, 2021. Virtual.
Undergraduate Publications:
- Brown TG, Xu J, Hurd YL, Pan YX. Dysregulated expression of the alternatively spliced variant mRNAs of the mu opioid receptor gene, OPRM1, in the medial prefrontal cortex of male human heroin abusers and heroin self-administering male rats. J Neurosci Res. 2020 Jun 7:10.1002/jnr.24640.
- Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, Pan YX.Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. J Clin Invest. 2017 Apr 3;127(4):1561-1573.
- Xu J, Xu M, Brown T, Rossi GC, Hurd YL, Inturrisi CE, Pasternak GW, Pan YXStabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action. J Biol Chem. 2013 Jul 19;288(29):21211-21227.
